It is proposed that UBOs “Unidentified Bright Objects” be a diagnostic criterion for NF1 since 43%-93% of NF children will exhibit areas of increased T2-weighted signal intensity on MRI screenings.
Recent Journal Abstracts (Full Text where available) regarding UBOs are listed below:
© 2000 American Academy of Neurology
K. DeBella, BSc, K. Poskitt, MD, J. Szudek, BSc and J. M. Friedman, MD, PhD
From the Department of Medical Genetics (K. DeBella, J. Szudek, and Dr. Friedman), The University of British Columbia; and Department of Radiology (Dr. Poskitt), BC’s Children’s Hospital, Vancouver, British Columbia, Canada.
Rosenbaum T, Engelbrecht V, Krolls W, van Dorsten FA, Hoehn-Berlage M, Lenard HG.
Am J Med Genet 1996 Feb 16;67(1):98-102
Denckla MB, Hofman K, Mazzocco MM, Melhem E, Reiss AL, Bryan RN, Harris EL, Lee J, Cox CS, Schuerholz LJ.